Injectable fillers are a great and relatively non-invasive way to reverse the signs of aging. Radiesse is an injectable filler that works well for treating and correcting the deep wrinkles and folds between the mouth and cheek (nasolabial folds and marionette lines). Dr. Smith performs this procedure on patients in the office under local anesthesia. The procedure usually takes 30 minutes. Typically the results last between 18 and 36 months.